Smoke purification and filtration system can effectively absorb and filter the smoke and dust generated in the process of welding, laser marking, laser engraving, etc., and at the same time play a role in the adsorption and thorough filtration of toxic and harmful gases and dusts, such as hydrocarbons and cyanide compounds, to prevent environmental pollution. Three layers of filtration devices are usually used, including primary filtration, intermediate filtration and main filtration, to ensure the filtration of harmful substances in the smoke and protect human safety. The primary filter, intermediate filter and main filter can be replaced individually, which can maximize the use of filters and reduce production and use costs.